2012/01/24 16:46 に 特定非営利活動法人京都SMI が投稿
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2012/01/28 20:20 に更新しました
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開催概要 - 演題: ”Genetic Engineering of Cells and Animal Models using Zinc Finger Nuclease Technology”
- 講師: Trevor N. Collingwood, PhD (Manager, Technology Research, Research Biotech, SIGMA-Aldrich Co. LLC)
- 日時: 平成24年2月3日(金) 16:30-18:10
- 会場: 京都大学 物質-細胞統合システム拠点(iCeMS=アイセムス) 本館2階セミナー室
内容 Zinc
Finger Nucleases (ZFNs) are a class of engineered DNA binding proteins that
enable targeted modification of the genome by creating site-specific
double-strand DNA breaks. The cell’s natural DNA repair processes are then
harnessed and controlled to create the desired genomic modification. This
approach enables highly efficient targeted gene knockout, point mutation and
gene insertion at endogenous loci ZFN technology has been applied to a broad
array of cell types for many purposes including understanding basic protein
function, creating isogenic cell line models of human disease, tagging of
endogenous genes with fluorescent markers. Recent advances in ZFN technology
and how it can be applied are opening further opportunities for sophisticated
genomic engineering
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